Akurasi Biopsi Aspirasi Jarum Halus untuk Diagnostik Tumor Kelenjar Liur di RSUD DR Saiful Anwar Malang 2018-2022

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Fitria Mayasari
Universitas Brawijaya, Malang, Indonesia
Muhammad Luqman Fadli
Universitas Brawijaya, Malang, Indonesia
Nia Kania
Universitas Lambung Mangkurat, Banjarmasin, Indonesia

Fine needle aspiration biopsy is accepted as a safe, reliable, minimally invasive, and cost-effective method. Fine needle aspiration biopsy aims to assist clinicians in handling patients. The purpose of this study is to evaluate the validity of fine needle aspiration biopsy as a diagnostic tool in salivary gland tumors compared to histopathological examination at Dr. Saiful Anwar Malang Hospital for the period of 2018-2022. Methods: Fine needle aspiration biopsy examination was performed before surgery, then compared with the results of histopathological examination after surgery as gold standard and retrospectively reviewed. Fine needle aspiration biopsy results and histopathological results are classified as neoplasm or non-neoplasm and benign or malignant. Validity is determined from sensitivity, specificity, positive conjecture value, negative conjecture value and accuracy. As a result, there were 33 cases of salivary gland tumors that met the inclusion criteria in the period 2018-2022 were reviewed, then classified into neoplasms or non-neoplasms and benign or malignant neoplasms. The sensitivity, specificity, accuracy, positive presumptive value, and negative presumptive value of cytological diagnosis of fine needle aspiration biopsy of salivary gland tumors for the neoplasm or non-neoplasm category were 93.1%, 100%, 93.9%, 100%, 66.7% and for the benign or malignant category 94.4%, 88.9%, 92.6%, 94.4%, 88.9%. This study shows that salivary gland fine needle aspiration biopsy cytology is a reliable and accurate diagnostic method for the diagnosis of salivary gland lesions. Conclusions: Fine needle aspiration biopsy is a useful method for diagnostics in salivary gland tumors but cannot replace histopathological examination as the gold standard for diagnostics.


Keywords: Salivary Glands, Fine Needle Aspiration Biopsy, Histopathology, Accuracy
Cahyati, Miftakhul, & Septina, Farihah. (2023). Tips dan Trik Klinis Radiografis Mendeteksi Abnormalitas Kelenjar Saliva. Universitas Brawijaya Press.
Collazo-Fernández, Lucía, Campo-Trapero, Julián, Cano-Sánchez, Jorge, García-Martín, Rosa, & Ballestín-Carcavilla, Claudio. (2017). Retrospective study of 149 cases of salivary gland carcinoma in a Spanish hospital population. Medicina Oral, Patologia Oral y Cirugia Bucal, 22(2), e207.
Cunha, John Lennon Silva, Hernandez-Guerrero, Juan Carlos, de Almeida, Oslei Paes, Soares, Ciro Dantas, & Mosqueda-Taylor, Adalberto. (2021). Salivary gland tumors: a retrospective study of 164 cases from a single private practice service in Mexico and literature review. Head and Neck Pathology, 15, 523–531.
da Silva, Leorik Pereira, Serpa, Marianna Sampaio, Viveiros, Stephanie Kenig, Sena, Dáurea Adília Cóbe, de Carvalho Pinho, Rodrigo Finger, de Abreu Guimarães, Letícia Drumond, de Sousa Andrade, Emanuel Sávio, Pereira, José Ricardo Dias, da Silveira, Márcia Maria Fonseca, & Sobral, Ana Paula Veras. (2018). Salivary gland tumors in a Brazilian population: A 20-year retrospective and multicentric study of 2292 cases. Journal of Cranio-Maxillofacial Surgery, 46(12), 2227–2233.
Firmansyah, Muhammad Lukman, Fadli, Muhammad, & Retnani, Diah. (2023). Penelitian Retrospektif Profil Klinikopatologi Tumor Kelenjar Liur di Instalasi Patologi Anatomi RSUD Dr. Saiful Anwar Malang Periode Tahun 2017-2021. Jurnal Klinik Dan Riset Kesehatan, 3(1), 9–17.
Ginano, Nurintan Kasmin, Muis, Mirna, & Murtala, Bachtiar. (2018). Kesesuaian Ct Scan Leher dengan Hasil Biopsi Aspirasi Jarum Halus dalam Mengidentifikasi Keganasan Limfadenopati Leher. Mandala Of Health, 11(2), 95–102.
Hafez, Nesreen H., & Abusinna, Eman S. (2020). Risk assessment of salivary gland cytological categories of the Milan system: a retrospective cytomorphological and immunocytochemical institutional study. Turkish Journal of Pathology, 36(2), 142.
Jeferson, Elvis, & Faruk, Muhammad. (2021). Epidemiology major salivary gland tumour in Eastern Indonesia. International Journal of Medical Reviews and Case Reports, 5(1), 114.
Karuna, Veer, Gupta, Priya, Rathi, Monika, Grover, Kriti, Nigam, Jitendra Singh, & Verma, Nidhi. (2019). Effectuation to Cognize malignancy risk and accuracy of fine needle aspiration cytology in salivary gland using “Milan System for Reporting Salivary Gland Cytopathology”: A 2 years retrospective study in academic institution. Indian Journal of Pathology and Microbiology, 62(1), 11–16.
Manatar, Amelia Fossetta. (2022). Diagnostic Accuracy and Analysis of Cytomorphological Images of Fine Needle Aspiration Biopsy in Salivary Gland Lesions Based on The Milan System for Reporting Salivary Gland Cytology (MSRSGC) Classification. Majalah Patologi Indonesia, 31(3). https://doi.org/10.55816/mpi.v31i3.517
Merung, Marcella P. J. (2014). GAMBARAN HISTOPATOLOGI TUMOR KELENJAR LIUR DI MANADO PERIODE JULI 2010 –JULI 2013. E-CliniC, 2(1).
Timoshenko, Artem, & Hauser, John R. (2019). Identifying customer needs from user-generated content. Marketing Science, 38(1), 1–20.
Wang, Xiao dong, Meng, Ling jiao, Hou, Ting ting, & Huang, Shao hui. (2015). Tumours of the salivary glands in northeastern China: a retrospective study of 2508 patients. British Journal of Oral and Maxillofacial Surgery, 53(2), 132–137.
Zuryani, Intan. (2023). Tumor Kelenjar Parotis. Antigen: Jurnal Kesehatan Masyarakat Dan Ilmu Gizi, 1(4), 77–94.